KOMISJA CHEMII I FIZYKI
W BIOLOGII I MEDYCYNIE
ODDZIAŁU POLSKIEJ AKADEMII
NAUK WE WROCŁAWIU

uprzejmie zaprasza

na posiedzenie naukowe, które odbędzie się w
poniedziałek 13 listopada 2023 r. o godz. 15.00
w sali 236, w budynku A2 Uniwersytetu Przyrodniczego we Wrocławiu
ul. Norwida 25 (sala seminaryjna – II piętro).
Podczas posiedzenia wykład pt.:

Milk protein-based carrier system for the encapsulation of dietary polyphenol rutin: molecular-level interactions and effects on bioactivities

wygłosi :
Priti Sengupta, PhD
from
Department of Chemistry, University of Calcutta, India

Abstract:
Rutin is an important class of polyphenols and has potential antioxidant, antitumor, and other bioactivities. However, the low water solubility, instability in the gastric/intestinal phase, etc., limit its practical applications by suppressing functional abilities and bioaccessibility. Encapsulation is the well-proven process that improves the water solubility of hydrophobic polyphenols and hence has a positive impact on their bioactivity. The self-assembly process of proteins provides plenty of potential for redesigning and combining them into supramolecular assemblies for real-time applications. The present work demonstrates the encapsulation of rutin in milk-derived casein micelles followed by their molecular interactions and biological implications. The research focused on three important issues: the mechanism of interaction of rutin with the monomeric milk protein; the impact of encapsulation of rutin on its bioactivities; the release rate and corresponding kinetics of rutin from the micellar system.

Przewodnicząca Komisji
Chemii i Fizyki w Biologii i Medycynie
Dr hab. Hanna Pruchnik